Glassy phases in random heteropolymers with correlated sequences
نویسندگان
چکیده
منابع مشابه
Freezing of compact random heteropolymers with correlated sequence fluctuations
Random heteropolymers ~RHPs! with uncorrelated sequence fluctuations on the segmental scale can undergo a transition wherein, below a certain temperature, the thermodynamics is determined by a few dominant conformations. We study this ‘‘freezing’’ transition for RHPs with correlated sequence fluctuations. Specifically, we apply our theory to the case where the correlations decay with a single c...
متن کاملCorrelated energy landscape model for finite, random heteropolymers.
In this paper, we study the role of correlations in the energy landscape of a finite random heteropolymer by developing the mapping onto the generalized random energy model ~GREM! proposed by Derrida and Gardner @J. Phys. C 19, 2253 ~1986!# in the context of spin glasses. After obtaining the joint distribution for energies of pairs of configurations, and by calculating the entropy of the polyme...
متن کاملMechanical response of random heteropolymers
We present an analytical theory for heteropolymer deformation, as exemplified experimentally by stretching of single protein molecules. Using replica mean-field theory, we determine phase diagrams for stress-induced unfolding of typical random sequences. This transition is sharp in the limit of infinitely long chain molecules. However, for chain lengths relevant to biological macromolecules, pa...
متن کاملReversible stretching of random heteropolymers.
We analyze the equilibrium response of random heteropolymers to mechanical deformation. In contrast to homopolymer response, the stress-induced transformation of a heteropolymer from globule to coil need not be sharp. For chain lengths relevant to biological macromolecules, intermediate necklace-like structures dominate over a range of applied force. Stability of these conformations is primaril...
متن کاملPhase diagram of random heteropolymers.
We propose a new analytic approach to study the phase diagram of random heteropolymers, based on the cavity method. For copolymers we analyze the nature and phenomenology of the glass transition as a function of sequence correlations. Depending on these correlations, we find that two different scenarios for the glass transition can occur. We show that, beside the much studied possibility of an ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Chemical Physics
سال: 2004
ISSN: 0021-9606,1089-7690
DOI: 10.1063/1.1738639